Sema3e^em2(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Sema3e^em2(IMPC)H
• Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6367946
• Gene: Sema3e Location: Chr5:14075290-14306703 bp, + strand Genetic Position: Chr5, 5.66 cM
• Alliance: Sema3e^em2(IMPC)H page
• IMPC: Sema3e gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 Protein and 4 guide sequences CCTCTTATAGTCTTCAACTAGAA, CCTCAACTTTTCCACGGTCCACA, CCAGGACCTTGCTTCAAATCCGC, CCTCGTGCTGCAGTCACTCGTGC, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema3e Mutation: 70 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 1 reference(s)