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Ccl28tm1Takna
Targeted Allele Detail
Nomenclature
Symbol: Ccl28tm1Takna
Name: chemokine (C-C motif) ligand 28; targeted mutation 1, Takashi Nakayama
MGI ID: MGI:6367826
Gene: Ccl28  Location: Chr13:119623819-119654359 bp, + strand  Genetic Position: Chr13, Syntenic
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:256896
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intergenic deletion
 
Mutation detailsExon 1 was replaced with a gene cassette encoding enhanced GFP and the neomycin resistance gene. RT-PCR confirmed absence of mRNA in mucosal tissues. EGFP expression is undetectable in mucosal tissues. (J:256896)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccl28 Mutation:  3 strains or lines available
References
Original:  J:256896 Matsuo K, et al., CCL28-Deficient Mice Have Reduced IgA Antibody-Secreting Cells and an Altered Microbiota in the Colon. J Immunol. 2018 Jan 15;200(2):800-809
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory