Uox^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Uox^tm1Itl
• Name: urate oxidase; targeted mutation 1, Ingenious Targeting Laboratory
• MGI ID: MGI:6364864
• Synonyms: floxed Uox
• Gene: Uox Location: Chr3:146302904-146337238 bp, + strand Genetic Position: Chr3, 72.09 cM
• Alliance: Uox^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278783
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sequences flank critical exons 3 and 4. No further details are specified. (J:278783)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Uox Mutation: 33 strains or lines available

References

• Original: J:278783 Chen X, et al., Dissociation between urate and blood pressure in mice and in people with early Parkinson's disease. EBioMedicine. 2018 Nov;37:259-268
• All: 1 reference(s)