Eif4ebp2tm1.1Nso
Targeted Allele Detail
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Symbol: |
Eif4ebp2tm1.1Nso |
Name: |
eukaryotic translation initiation factor 4E binding protein 2; targeted mutation 1.1, Nahum Sonenberg |
MGI ID: |
MGI:6364845 |
Synonyms: |
Eif4ebp2flx |
Gene: |
Eif4ebp2 Location: Chr10:61268276-61288448 bp, - strand Genetic Position: Chr10, 32.21 cM, cytoband B4-B5
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Alliance: |
Eif4ebp2tm1.1Nso page
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Germline Transmission: |
Earliest citation of germline transmission:
J:278826
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: Exon 2 was flanked by loxP sites and an frt-flanked neomycin selection cassette. The neomycin selection cassette was removed via Flp-mediated recombination in the germline.
(J:278826)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Eif4ebp2 Mutation: |
23 strains or lines available
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Original: |
J:278826 Wiebe S, et al., Inhibitory interneurons mediate autism-associated behaviors via 4E-BP2. Proc Natl Acad Sci U S A. 2019 Sep 3;116(36):18060-18067 |
All: |
4 reference(s) |
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