Cacng2^tm1Mwa
Targeted Allele Detail

Summary

• Symbol: Cacng2^tm1Mwa
• Name: calcium channel, voltage-dependent, gamma subunit 2; targeted mutation 1, Masahiko Watanabe
• MGI ID: MGI:6363971
• Synonyms: gamma-2 floxed
• Gene: Cacng2 Location: Chr15:77875948-78004228 bp, - strand Genetic Position: Chr15, 36.92 cM
• Alliance: Cacng2^tm1Mwa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:163029
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site and an frt flanked PGK-neomycin selection cassette were inserted 158 bp upstream of exon 3. A second loxP site was inserted 159 bp downstream of that same exon. (J:163029)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cacng2 Mutation: 26 strains or lines available

References

• Original: J:163029 Yamazaki M, et al., TARPs gamma-2 and gamma-7 are essential for AMPA receptor expression in the cerebellum. Eur J Neurosci. 2010 Jun;31(12):2204-20
• All: 2 reference(s)