Rr109^em4Abh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr109^em4Abh
• Name: regulatory region 109; endonuclease-mediated mutation 4, Avinash Bhandoola
• MGI ID: MGI:6363211
• Synonyms: Foxn1^deltaD, Foxn1^em4Abh
• Gene: Rr109 Location: unknown Genetic Position: Chr11, Syntenic
• Alliance: Rr109^em4Abh page

Mutation origin

• Strain of Origin: C57BL/6NCr

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting of a cis-regulatory element (RE) in intron 1 of the Foxn1 gene deleted chr11:78373791-78375465 (mm10). (J:278361)

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rr109 Mutation: 0 strains or lines available

References

• Original: J:278361 Larsen BM, et al., Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells. J Immunol. 2019 Aug 1;203(3):686-695
• All: 1 reference(s)