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Noc4ltm1.1Nju
Targeted Allele Detail
Nomenclature
Symbol: Noc4ltm1.1Nju
Name: NOC4 like; targeted mutation 1.1, Model Animal Research Center of Nanjing University
MGI ID: MGI:6362739
Gene: Noc4l  Location: Chr5:110648419-110653382 bp, - strand  Genetic Position: Chr5, 53.69 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:247476
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 3 and a FRT-flanked neomycin selection cassette and a second loxP site were inserted downstream of exon 3. Cre-mediated recombination deleted exon 3 and the selection cassette. (J:247476)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Noc4l Mutation:  19 strains or lines available
References
Original:  J:247476 Qin Y, et al., Targeted disruption of Noc4l leads to preimplantation embryonic lethality in mice. Protein Cell. 2017 Mar;8(3):230-235
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory