Rr111^tm2.1Ics
Targeted Allele Detail

Summary

• Symbol: Rr111^tm2.1Ics
• Name: regulatory region 111; targeted mutation 2.1, Mouse Clinical Institute
• MGI ID: MGI:6361937
• Synonyms: Egr2^tm2.1Ics, Krox20^deltaC
• Gene: Rr111 Location: unknown Genetic Position: Chr10, Syntenic
• Alliance: Rr111^tm2.1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:246865
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of Egr2 autoregulatory element C. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of the element. Cre-mediated recombination removed element C and the selection cassette. (J:243865)

Expression

In Mice Carrying this Mutation:

39 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr111 Mutation: 0 strains or lines available

References

• Original: J:243865 Thierion E, et al., Krox20 hindbrain regulation incorporates multiple modes of cooperation between cis-acting elements. PLoS Genet. 2017 Jul;13(7):e1006903
• All: 2 reference(s)