Ager^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Ager^tm1.1Geno
• Name: advanced glycosylation end product-specific receptor; targeted mutation 1.1, Genoway
• MGI ID: MGI:6361242
• Synonyms: Ager^flox
• Gene: Ager Location: Chr17:34816836-34819910 bp, + strand Genetic Position: Chr17, 18.18 cM
• Alliance: Ager^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278881
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site together with an frt-flanked neomycin selection cassette was inserted within intron 7 and a single distal loxP was inserted within intron 3 of the gene. The frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. (J:278881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ager Mutation: 32 strains or lines available

References

• Original: J:278881 Hurtado Del Pozo C, et al., A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis. Cell Rep. 2019 Jul 16;28(3):773-791.e7
• All: 2 reference(s)