Prss44<em1Osb> Endonuclease-mediated Allele Detail MGI Mouse (MGI:6361142)

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Prss44^em1Osb
Endonuclease-mediated Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Prss44^em1Osb
Name:	serine protease 44; endonuclease-mediated mutation 1, Research Institute for Microbial Diseases, Osaka University
MGI ID:	MGI:6361142
Gene:	Prss44 Location: Chr9:110642987-110647067 bp, + strand Genetic Position: Chr9, 60.79 cM
Alliance:	Prss44^em1Osb page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:279100
Parent Cell Line:	EGR-G101 (ES Cell)
Strain of Origin:	C57BL/6NSlc-Tg(CAG-EGFP,Acr-EGFP)2Osb

Mutation
description

Allele Type:		Endonuclease-mediated (Null/knockout)
Mutation:		Intragenic deletion
		CRISPR-targeting deleted the first through last coding exon (3293 bp). (J:279100)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available Cell Lines: 0 lines available
Carrying any Prss44 Mutation:	18 strains or lines available

References

Original:	J:279100 Holcomb RJ, et al., The testis-specific serine proteases Prss44, Prss46, and Prss54 are dispensable for mouse fertility. Biol Reprod. 2019 Aug 12;
All:	1 reference(s)

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