Speg^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Speg^tm1Itl
• Name: SPEG complex locus; targeted mutation 1, Ingenious Targeting Laboratory
• MGI ID: MGI:6360671
• Gene: Speg Location: Chr1:75351941-75408964 bp, + strand Genetic Position: Chr1, 38.88 cM
• Alliance: Speg^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:261744
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP/FRT flanked Neo cassette was inserted on the 5 side of exon 14 and a single loxP site was inserted between exons 17 and 18 of the gene. (J:261744)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Speg Mutation: 135 strains or lines available

References

• Original: J:261744 Huntoon V, et al., SPEG-deficient skeletal muscles exhibit abnormal triad and defective calcium handling. Hum Mol Genet. 2018 May 1;27(9):1608-1617
• All: 5 reference(s)