Fance^{Tg(Tyr)OVE2364E-2a2Chfu}
Transgenic Allele Detail

Summary

• Symbol: Fance^{Tg(Tyr)OVE2364E-2a2Chfu}
• Name: Fanconi anemia, complementation group E; transgene insertion OVE2364E-2a2, Chun Fu
• MGI ID: MGI:6359443
• Synonyms: Fance MT
• Gene: Fance Location: Chr17:28532504-28545548 bp, + strand Genetic Position: Chr17, 14.65 cM
• Alliance: Fance^{Tg(Tyr)OVE2364E-2a2Chfu} page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A self-inactivating lentivirus carrying a tyrosinase miningene was injected under the zona pellucida of FVB/N two-cell embryos. In line OVE2364E-2a2 the virus was determined to have been inserted into intron 8 of the Fanconi anemia complementation group E gene.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fance Mutation: 21 strains or lines available

References

• Original: J:251511 Fu C, et al., Dearth and Delayed Maturation of Testicular Germ Cells in Fanconi Anemia E Mutant Male Mice. PLoS One. 2016;11(8):e0159800
• All: 1 reference(s)