Efr3a^tm1.1Bgsn
Targeted Allele Detail

Summary

• Symbol: Efr3a^tm1.1Bgsn
• Name: EFR3 homolog A; targeted mutation 1.1, Binggui Sun
• MGI ID: MGI:6358568
• Gene: Efr3a Location: Chr15:65658883-65745665 bp, + strand Genetic Position: Chr15, 29.12 cM
• Alliance: Efr3a^tm1.1Bgsn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:273434
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed the selection cassette and exon 2. (J:273434)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efr3a Mutation: 56 strains or lines available

References

• Original: J:273434 Hu H, et al., Efr3a Insufficiency Attenuates the Degeneration of Spiral Ganglion Neurons after Hair Cell Loss. Front Mol Neurosci. 2017;10:86
• All: 1 reference(s)