Alg13^em1Bayu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Alg13^em1Bayu
• Name: asparagine-linked glycosylation 13; endonuclease-mediated mutation 1, Baoli Yu
• MGI ID: MGI:6358168
• Gene: Alg13 Location: ChrX:143100962-143157446 bp, + strand Genetic Position: ChrX, 65.42 cM, cytoband F2
• Alliance: Alg13^em1Bayu page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology deleted 5 nucleotides (TTCAT) in the 4th exon. Immunohistochemistry and Western blot analysis confirmed absence of protein. (J:275180)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Alg13 Mutation: 196 strains or lines available

References

• Original: J:275180 Gao P, et al., ALG13 Deficiency Associated with Increased Seizure Susceptibility and Severity. Neuroscience. 2019 Mar 12
• All: 1 reference(s)