Gmnn^tm1Mkss
Targeted Allele Detail

Summary

• Symbol: Gmnn^tm1Mkss
• Name: geminin; targeted mutation 1, Michael Kessel
• MGI ID: MGI:6358051
• Synonyms: Gmnn^fl
• Gene: Gmnn Location: Chr13:24935828-24945906 bp, - strand Genetic Position: Chr13, 10.64 cM
• Alliance: Gmnn^tm1Mkss page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:234756
• Parent Cell Line: MPI-II (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The first loxP site was inserted 143 bps upstream of exon 2, the second loxP site, together with a frt-site flanked neomycin cassette, 182 bps downstream of exon 3. (J:234756)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gmnn Mutation: 26 strains or lines available

References

• Original: J:234756 Tabrizi GA, et al., Geminin is required for the maintenance of pluripotency. PLoS One. 2013;8(9):e73826
• All: 1 reference(s)