Rgs7bp^tm1.1Kjp
Targeted Allele Detail

Summary

• Symbol: Rgs7bp^tm1.1Kjp
• Name: regulator of G-protein signalling 7 binding protein; targeted mutation 1.1, Kendall J Blumer
• MGI ID: MGI:6358035
• Gene: Rgs7bp Location: Chr13:105082412-105191438 bp, - strand Genetic Position: Chr13, 56.9 cM, cytoband D1
• Alliance: Rgs7bp^tm1.1Kjp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:192325
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 2 was flanked by loxP sites and a neomycin selection cassette. Exon 2 was subsequently deleted following cre-mediated recombination of the flanking loxP sites in the germline. (J:192325)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgs7bp Mutation: 18 strains or lines available

References

• Original: J:192325 Zhou H, et al., GIRK channel modulation by assembly with allosterically regulated RGS proteins. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):19977-82
• All: 2 reference(s)