Mapttm1(Mecp2)Bird
Targeted Allele Detail
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Symbol: |
Mapttm1(Mecp2)Bird |
Name: |
microtubule-associated protein tau; targeted mutation 1, Adrian Bird |
MGI ID: |
MGI:6357819 |
Synonyms: |
Tau-Mecp2 |
Gene: |
Mapt Location: Chr11:104122216-104222916 bp, + strand Genetic Position: Chr11, 67.79 cM, cytoband E1
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Alliance: |
Mapttm1(Mecp2)Bird page
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Germline Transmission: |
Earliest citation of germline transmission:
J:272570
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Parent Cell Line: |
E14TG2a (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready, Inserted expressed sequence) |
Mutation: |
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Insertion
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Mutation details: The targeting construct introduced upstream of exon 2 a loxP site, wild-type cDNA, SV40 polyadenylation sequence, loxP site and selection cassette.
(J:272570)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Mapt Mutation: |
428 strains or lines available
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Original: |
J:272570 Koerner MV, et al., Toxicity of overexpressed MeCP2 is independent of HDAC3 activity. Genes Dev. 2018 Dec 1;32(23-24):1514-1524 |
All: |
1 reference(s) |
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