Wdr62^tm1.1Zhxu
Targeted Allele Detail

Summary

• Symbol: Wdr62^tm1.1Zhxu
• Name: WD repeat domain 62; targeted mutation 1.1, Zhiheng Xu
• MGI ID: MGI:6357701
• Gene: Wdr62 Location: Chr7:29939563-29979844 bp, - strand Genetic Position: Chr7, 17.34 cM
• Alliance: Wdr62^tm1.1Zhxu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:266305
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Cre-mediated recombination removed exon 2 and the selection cassette. (J:266305)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr62 Mutation: 47 strains or lines available

References

• Original: J:266305 Zhou Y, et al., Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans. PLoS Genet. 2018 Aug;14(8):e1007463
• All: 4 reference(s)