Prm2^em1Kyot
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prm2^em1Kyot
• Name: protamine 2; endonuclease-mediated mutation 1, Katsuhiko Itoh
• MGI ID: MGI:6357204
• Synonyms: Prm2^S56A
• Gene: Prm2 Location: Chr16:10609241-10609969 bp, - strand Genetic Position: Chr16, 5.84 cM
• Alliance: Prm2^em1Kyot page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• CRISPR-Cas9 mediated mutagenesis induced a codon switch from Ser56 to alanine. (J:278367)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prm2 Mutation: 8 strains or lines available

References

• Original: J:278367 Itoh K, et al., Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo. Sci Signal. 2019 Mar 26;12(574)
• All: 1 reference(s)