Rnd3^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Rnd3^tm1Itl
• Name: Rho family GTPase 3; targeted mutation 1, Ingenious Targeting Laboratory
• MGI ID: MGI:6356870
• Gene: Rnd3 Location: Chr2:51020451-51039123 bp, - strand Genetic Position: Chr2, 29.63 cM
• Alliance: Rnd3^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:278286
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP-flanked Neo cassette was inserted on the 3 side of exon 2 and the single loxP site was inserted at the 5 side of exon 1. (J:278286)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnd3 Mutation: 28 strains or lines available

References

• Original: J:278286 Miyazaki Y, et al., Zyxin modulates the transmigration of Haemophilus influenzae to the central nervous system. Virulence. 2014 Aug 15;5(6):665-72
• All: 2 reference(s)