Kirrel1^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Kirrel1^tm1.1Geno
• Name: kirre like nephrin family adhesion molecule 1; targeted mutation 1.1, Genoway
• MGI ID: MGI:6356794
• Synonyms: Neph1^fl
• Gene: Kirrel1 Location: Chr3:86985900-87082054 bp, - strand Genetic Position: Chr3, 38.18 cM, cytoband F1
• Alliance: Kirrel1^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:241326
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exons 12-15 were flanked by loxP sites and an frt-flanked neomycin selection cassette. The neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:241326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kirrel1 Mutation: 194 strains or lines available

References

• Original: J:241326 Grahammer F, et al., A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. JCI Insight. 2016 Jun 16;1(9)
• All: 1 reference(s)