Micu1^tm1.1Itl
Targeted Allele Detail

Summary

• Symbol: Micu1^tm1.1Itl
• Name: mitochondrial calcium uptake 1; targeted mutation 1.1, Ingenious Targeting Laboratory
• MGI ID: MGI:6356790
• Gene: Micu1 Location: Chr10:59538385-59699956 bp, + strand Genetic Position: Chr10, 29.6 cM
• Alliance: Micu1^tm1.1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:236567
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites and an frt-flanked neomycin selection cassette were inserted at sites flanking exon 3. The neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:236567)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Micu1 Mutation: 43 strains or lines available

References

• Original: J:236567 Antony AN, et al., MICU1 regulation of mitochondrial Ca(2+) uptake dictates survival and tissue regeneration. Nat Commun. 2016 Mar 09;7:10955
• All: 5 reference(s)