Tbx5^tm1.1Flc
Targeted Allele Detail

Summary

• Symbol: Tbx5^tm1.1Flc
• Name: T-box 5; targeted mutation 1.1 Frank Conlon
• MGI ID: MGI:6355944
• Synonyms: Tbx5^Avi
• Gene: Tbx5 Location: Chr5:119970733-120023284 bp, + strand Genetic Position: Chr5, 60.42 cM
• Alliance: Tbx5^tm1.1Flc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240078
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The biotin acceptor peptide (Avi) targeting cassette was inserted in frame to the terminal exon of the gene. A loxP-flanked neomycin selection cassette was removed via Cre-mediated recombination in the germline. (J:240078)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tbx5 Mutation: 28 strains or lines available

References

• Original: J:240078 Waldron L, et al., The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation. Dev Cell. 2016 Feb 08;36(3):262-75
• All: 1 reference(s)