Gla^em2(IMPC)H
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gla^em2(IMPC)H
• Name: galactosidase, alpha; endonuclease-mediated mutation 2, Harwell
• MGI ID: MGI:6355923
• Gene: Gla Location: ChrX:133488912-133501707 bp, - strand Genetic Position: ChrX, 56.2 cM, cytoband E-F1
• Alliance: Gla^em2(IMPC)H page
• IMPC: Gla gene page

Mutation origin

• Strain of Origin: C57BL/6NTac
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from IMPC was generated at Medical Research Council Harwell by injecting CAS9 Protein and 4 guide sequences TCTCACTTGTCCATCTGGTTTGG, GCTATTGAGGAGACCAAAACCGG, ATTGAGGAGACCAAAACCGGAGG, TACGGTCTCACTTGTCCATCTGG, which resulted in a Exon Deletion. (J:265051)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gla Mutation: 21 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 1 reference(s)