Rbmxl2^tm1.1Dell
Targeted Allele Detail

Summary

• Symbol: Rbmxl2^tm1.1Dell
• Name: RNA binding motif protein, X-linked-like 2; targeted mutation 1.1, David J Elliott
• MGI ID: MGI:6355367
• Synonyms: Rbmxl2^LoxP
• Gene: Rbmxl2 Location: Chr7:106808652-106810123 bp, + strand Genetic Position: Chr7, 56.1 cM
• Alliance: Rbmxl2^tm1.1Dell page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:275203
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The entire coding sequence was flanked by loxP sites and an FRT-flanked neomycin selection caseette. The selection cassette was removed via FLP-mediated recombination in the germline. (J:275203)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rbmxl2 Mutation: 10 strains or lines available

References

• Original: J:275203 Ehrmann I, et al., An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning. Elife. 2019 Jan 24;8:e39304
• All: 1 reference(s)