Nipbl^tm1Fsp
Targeted Allele Detail

Summary

• Symbol: Nipbl^tm1Fsp
• Name: NIPBL cohesin loading factor; targeted mutation 1, Francois Spitz
• MGI ID: MGI:6343216
• Synonyms: Nipbl^flox
• Gene: Nipbl Location: Chr15:8320101-8473947 bp, - strand Genetic Position: Chr15, 3.82 cM, cytoband A2
• Alliance: Nipbl^tm1Fsp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:250426
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Two loxP sites flank exon 18. (J:250426)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nipbl Mutation: 124 strains or lines available

References

• Original: J:250426 Schwarzer W, et al., Two independent modes of chromatin organization revealed by cohesin removal. Nature. 2017 Nov 2;551(7678):51-56
• All: 1 reference(s)