Recql4^m2Anu
Chemically induced Allele Detail

Summary

• Symbol: Recql4^m2Anu
• Name: RecQ protein-like 4; mutation 2, Australian National University
• MGI ID: MGI:6342636
• Synonyms: Recql4 R347*
• Gene: Recql4 Location: Chr15:76587753-76594748 bp, - strand Genetic Position: Chr15, 36.28 cM, cytoband D3
• Alliance: Recql4^m2Anu page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: APF ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to A point mutation at position 1122 of cDNA (ENSMUST00000036852) in exon 5 that results in the amino acid substitution of an arginine to a STOP at position 347 (R347X). (J:277473)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Recql4 Mutation: 53 strains or lines available

References

• Original: J:277473 Castillo-Tandazo W, et al., ATP-dependent helicase activity is dispensable for the physiological functions of Recql4. PLoS Genet. 2019 Jul;15(7):e1008266
• All: 2 reference(s)