P4htm^tm1Soin
Targeted Allele Detail

Summary

• Symbol: P4htm^tm1Soin
• Name: prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum); targeted mutation 1, Raija Soininen
• MGI ID: MGI:6342508
• Gene: P4htm Location: Chr9:108456061-108474866 bp, - strand Genetic Position: Chr9, 59.52 cM
• Alliance: P4htm^tm1Soin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237953
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• A lacZ/neo cassette was inserted into exon 3 of the gene. (J:237953)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any P4htm Mutation: 70 strains or lines available

References

• Original: J:237953 Leinonen H, et al., Lack of P4H-TM in mice results in age-related retinal and renal alterations. Hum Mol Genet. 2016 Sep 01;25(17):3810-3823
• All: 2 reference(s)