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Ago2tm1.1Doca
Targeted Allele Detail
Summary
Symbol: Ago2tm1.1Doca
Name: argonaute RISC catalytic subunit 2; targeted mutation 1.1, Donal OCarroll
MGI ID: MGI:6336157
Synonyms: Ago2S388A
Gene: Ago2  Location: Chr15:72967693-73056777 bp, - strand  Genetic Position: Chr15, 33.92 cM
Alliance: Ago2tm1.1Doca page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:82809
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Not Specified)
Mutation:    Nucleotide substitutions
 
Mutation detailsTwo point mutations in exon 10, converting Serine 388 in an Alanine residue. Residual LoxP site between exon 8 and 9 due to removal of neomycin resistance cassette. (J:82809)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Ago2 Mutation:  54 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory