Krt86^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Krt86^em1(IMPC)Tcp
• Name: keratin 86; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:6324176
• Gene: Krt86 Location: Chr15:101371359-101377864 bp, + strand Genetic Position: Chr15, 56.9 cM
• Alliance: Krt86^em1(IMPC)Tcp page
• IMPC: Krt86 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at The Centre for Phenogenomics using Cas9 and guides with spacer sequences ATTTGATACCAACCTCATCT, GTCCTGATAGGTCTTTCTGG, TCGCTCTAAGGCTGCCTACG, and TTAGGTCAAAGGTTACATCA that targeted exon(s) ENSMUSE00001071204.2 ENSMUSE00001074075.2 ENSMUSE00001084793.2 ENSMUSE00001091947.2 ENSMUSE00001092798.2. This resulted in deletion(s) of 2491 bp (location: Chr15:101373088-101375578; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Krt86 Mutation: 21 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 4 reference(s)