Sqstm1^tm1Biat
Targeted Allele Detail

Summary

• Symbol: Sqstm1^tm1Biat
• Name: sequestosome 1; targeted mutation 1, Biomodels Austria
• MGI ID: MGI:6317417
• Synonyms: P62^fl, p62^floxed
• Gene: Sqstm1 Location: Chr11:50090193-50101654 bp, - strand Genetic Position: Chr11, 30.36 cM, cytoband B1.2
• Alliance: Sqstm1^tm1Biat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:276619
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites flank exons 1-4. Cre-mediated recombination removed the slection cassette. (J:82809, J:276619)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Sqstm1 Mutation: 32 strains or lines available

References

• Original: J:276619 Lahiri P, et al., p62/Sequestosome-1 Is Indispensable for Maturation and Stabilization of Mallory-Denk Bodies. PLoS One. 2016;11(8):e0161083
• All: 3 reference(s)