Lgi1^tm1Ics
Targeted Allele Detail

Summary

• Symbol: Lgi1^tm1Ics
• Name: leucine-rich repeat LGI family, member 1; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:6317397
• Synonyms: LGI1^loxP
• Gene: Lgi1 Location: Chr19:38253135-38297387 bp, + strand Genetic Position: Chr19, 32.9 cM
• Alliance: Lgi1^tm1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182795
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites flank exons 6-7 of the gene. (J:182795)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lgi1 Mutation: 32 strains or lines available

References

• Original: J:182795 Chabrol E, et al., Electroclinical characterization of epileptic seizures in leucine-rich, glioma-inactivated 1-deficient mice. Brain. 2010 Sep;133(9):2749-62
• All: 2 reference(s)