Mtmr4^em1Adiuj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mtmr4^em1Adiuj
• Name: myotubularin related protein 4; endonuclease-mediated mutation 1, MODEL-AD Center
• MGI ID: MGI:6316317
• Synonyms: Mtmr4^V297G
• Gene: Mtmr4 Location: Chr11:87482988-87507128 bp, + strand Genetic Position: Chr11, 52.15 cM, cytoband C
• Alliance: Mtmr4^em1Adiuj page

Mutation origin

• Strain of Origin: B6(SJL)-Apoe^{tm1.1(APOE*4)Adiuj} Trem2^em1Adiuj/J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• CRISPR/Cas9 genome editing is used to introduce a V297G point mutation into the Mtmr4 gene. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mtmr4 Mutation: 64 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)