Cdk4^{tm1c(NCOM)Mfgc}
Targeted Allele Detail

Summary

• Symbol: Cdk4^{tm1c(NCOM)Mfgc}
• Name: cyclin dependent kinase 4; targeted mutation 1c, Mammalian Functional Genomics Centre
• MGI ID: MGI:6316287
• Synonyms: Cdk4^fl
• Gene: Cdk4 Location: Chr10:126899404-126903157 bp, + strand Genetic Position: Chr10, 74.5 cM, cytoband D3
• Alliance: Cdk4^{tm1c(NCOM)Mfgc} page
• IMPC: Cdk4 gene page

Mutation origin

• Mutant Cell Line: M00049_C_390W_F08
• Germline Transmission: Earliest citation of germline transmission: J:200814
• Parent Cell Line: C2 (Tcp) (ES Cell)
• Strain of Origin: C57BL/6N
• Project Collection: NorCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_MFGC3
• Mutation details: The Cdk4^{t1a(NCOM)Mfgc} allele (MGI:5766036) was FLP excised removing the neo selection cassette and lacZ reporter leaving behind the floxed critical exon(s). Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.knockoutmouse.org/about/targeting-strategies. (J:200814)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cdk4 Mutation: 57 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 2 reference(s)