Ptprs^{tm1c(KOMP)Mbp}
Targeted Allele Detail

Summary

• Symbol: Ptprs^{tm1c(KOMP)Mbp}
• Name: protein tyrosine phosphatase receptor type S; targeted mutation 1c, Mouse Biology Program, UC Davis
• MGI ID: MGI:6316283
• Gene: Ptprs Location: Chr17:56719426-56783480 bp, - strand Genetic Position: Chr17, 29.32 cM
• Alliance: Ptprs^{tm1c(KOMP)Mbp} page
• IMPC: Ptprs gene page

Mutation origin

• Mutant Cell Line: DEPD00535_1_D11
• Germline Transmission: Earliest citation of germline transmission: J:200814
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: KOMP-CSD

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion Vector: L1L2_Bact_P
• Mutation details: The Ptprs^{tm1a(KOMP)Mbp} allele (MGI:4840831) was FLP excised by microinjecting 100ng/ul of FLP mRNA (Miltenyi BIotec Inc.Cat# 130-106-769) into the cytoplasm of IVF-derived zygotes. This resulted in the removal of the neo selection cassette and lacZ reporter leaving behind the floxed critical exon(s). See http://www.mousephenotype.org/data/genes/MGI:97815 for more information. (J:200814)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ptprs Mutation: 78 strains or lines available

References

• Original: J:200814 Toronto Centre for Phenogenomics, Strains and alleles submitted by Toronto Centre for Phenogenomics (NorCOMM2, funded by Genome Canada and Ontario Genomics Institute OGI-051). MGI Direct Data Submission. 2013
• All: 6 reference(s)