Asah1^tm2Esc
Targeted Allele Detail

Summary

• Symbol: Asah1^tm2Esc
• Name: N-acylsphingosine amidohydrolase 1; targeted mutation 2, Edward H Schuchman
• MGI ID: MGI:6306953
• Synonyms: ASAH1^flox
• Gene: Asah1 Location: Chr8:41793234-41827810 bp, - strand Genetic Position: Chr8, 23.89 cM
• Alliance: Asah1^tm2Esc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:275291
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 9. An FRT-flanked neomycin resistance cassette was insered into intron 10. a additional loxP site was inserted downstream of exon 13. (J:275291)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asah1 Mutation: 43 strains or lines available

References

• Original: J:275291 Eliyahu E, et al., Construction of conditional acid ceramidase knockout mice and in vivo effects on oocyte development and fertility. Cell Physiol Biochem. 2012;30(3):735-48
• All: 3 reference(s)