Fgfbp1^tm1.2Wlstn
Targeted Allele Detail

Summary

• Symbol: Fgfbp1^tm1.2Wlstn
• Name: fibroblast growth factor binding protein 1; targeted mutation 1.2, Anton Wellstein
• MGI ID: MGI:6303583
• Synonyms: Fgfbp1^gfp
• Gene: Fgfbp1 Location: Chr5:44136200-44139121 bp, - strand Genetic Position: Chr5, 23.95 cM
• Alliance: Fgfbp1^tm1.2Wlstn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:251763
• Parent Cell Line: iTL BA1 (ES Cell)
• Strain of Origin: (C57BL/6NTac x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector was designed to insert a loxP site upstream of the entire coding region. A second loxP site and a frt site, followed by neomycin selection cassette (neo), a third loxP site, and a green fluorescent protein (GFP) sequence followed by a second frt site, were inserted downstream of the gene. Cre-mediated recombination removed the selection cassette. (J:251763)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgfbp1 Mutation: 22 strains or lines available

References

• Original: J:251763 Schmidt MO, et al., The Role of Fibroblast Growth Factor-Binding Protein 1 in Skin Carcinogenesis and Inflammation. J Invest Dermatol. 2018 Jan;138(1):179-188
• All: 1 reference(s)