Tg(Slx-Spo11*)1Mjn
Transgene Detail

Summary

• Symbol: Tg(Slx-Spo11*)1Mjn
• Name: transgene insertion 1, Maria Jasin
• MGI ID: MGI:6296590
• Synonyms: Tg(Xmr-Spo11betaB), Tg(Xmr-Spo11betaB)Xb3-8M
• Transgene: Tg(Slx-Spo11*)1Mjn Location: unknown
• Alliance: Tg(Slx-Spo11*)1Mjn page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Slx-Spo11*)1Mjn expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Spo11 (MGI:1349669)	Expresses beta isoform

• Tg(Slx-Spo11*)1Mjn expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slx (MGI:99543)

• Mutation details: A 1328 bp fragment containing a portion of the promoter and part of the 5 UTR of the Slx (Xmr) gene drives expression of the beta isoform of the mouse Spo11 cDNA in meiocytes. (J:169057)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:169057 Kauppi L, et al., Distinct properties of the XY pseudoautosomal region crucial for male meiosis. Science. 2011 Feb 18;331(6019):916-20
• All: 4 reference(s)