Bcl6^tm1Gdba
Targeted Allele Detail

Summary

• Symbol: Bcl6^tm1Gdba
• Name: B cell leukemia/lymphoma 6; targeted mutation 1, Grant D Barish
• MGI ID: MGI:6293908
• Synonyms: Bcl6^f, Bcl6^fl
• Gene: Bcl6 Location: Chr16:23783802-23807602 bp, - strand Genetic Position: Chr16, 15.26 cM
• Alliance: Bcl6^tm1Gdba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271078
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• LoxP sites were inserted between exons 5 and 6 via homologous recombination. (J:271078)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl6 Mutation: 55 strains or lines available

References

• Original: J:271078 Senagolage MD, et al., Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity. Cell Rep. 2018 Dec 18;25(12):3283-3298.e6
• All: 2 reference(s)