Tg(SLC15A1)1Dsmi
Transgene Detail

Summary

• Symbol: Tg(SLC15A1)1Dsmi
• Name: transgenic insertion 1, David E Smith
• MGI ID: MGI:6287835
• Synonyms: huPEPT1
• Transgene: Tg(SLC15A1)1Dsmi Location: unknown
• Alliance: Tg(SLC15A1)1Dsmi page

Transgene origin

• Strain of Origin: B6.129P2-Slc15a1^tm1Dgen

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(SLC15A1)1Dsmi expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SLC15A1 (6564)

  Slc15a1

  (MGI:1861376)

• Mutation details: The transgenic construct contains a human bacterial artificial chromosome (BAC) RP11-782G13 containing the human SLC15A1 (or PEPT1) gene including 5' regulatory elements, coding area, and 3' regulatory elements. The founder 1 contains one copy of the human BAC. (J:273387)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:273387 Hu Y, et al., Development and characterization of a novel mouse line humanized for the intestinal peptide transporter PEPT1. Mol Pharm. 2014 Oct 6;11(10):3737-46
• All: 4 reference(s)