Suv39h2^em1Ksz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Suv39h2^em1Ksz
• Name: suppressor of variegation 3-9 2; endonuclease-mediated mutation 1, Kenneth Zaret
• MGI ID: MGI:6287446
• Synonyms: Suv39h2^em1Jnw
• Gene: Suv39h2 Location: Chr2:3456852-3476068 bp, - strand Genetic Position: Chr2, 1.95 cM, cytoband A
• Alliance: Suv39h2^em1Ksz page

Mutation origin

• Strain of Origin: (C57BL/6J x C3H/HeJ)F1

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• CRISPR-targeting of exon 2 produced a null allele due to insertions and deletion of sequence. (J:271652)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Suv39h2 Mutation: 21 strains or lines available

References

• Original: J:271652 Nicetto D, et al., H3K9me3-heterochromatin loss at protein-coding genes enables developmental lineage specification. Science. 2019 Jan 18;363(6424):294-297
• All: 1 reference(s)