Gt(ROSA)26Sor^tm2Ndav
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm2Ndav
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Nadav Ahituv
• MGI ID: MGI:6287267
• Synonyms: R26P3^SCE2En-sgRNA
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm2Ndav page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:272371
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Not Applicable)
• Mutation: Insertion
• Mutation details: The targeting construction inserted into the locus a single guide RNA targeting Sim1 candidate enhancer 2 (SCE2). (J:272371)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1098 strains or lines available

References

• Original: J:272371 Matharu N, et al., CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. Science. 2019 Jan 18;363(6424)
• All: 1 reference(s)