Rgmb^tm1.1Jcfl
Targeted Allele Detail

Summary

• Symbol: Rgmb^tm1.1Jcfl
• Name: repulsive guidance molecule family member B; targeted mutation 1.1, Jean-Francois Cloutier
• MGI ID: MGI:6285616
• Gene: Rgmb Location: Chr17:16024923-16051508 bp, - strand Genetic Position: Chr17, 8.96 cM
• Alliance: Rgmb^tm1.1Jcfl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235517
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A tau-GFP reporter gene fusion was inserted in frame at the translation start site and deleted the endogenous signal sequence and all of exon 1. Flp-mediated recombination removed the neomycin resistance cassette. (J:235517)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rgmb Mutation: 13 strains or lines available

References

• Original: J:235517 Kam JW, et al., RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46
• All: 1 reference(s)