Ttn^tm4.1Hgra
Targeted Allele Detail

Summary

• Symbol: Ttn^tm4.1Hgra
• Name: titin; targeted mutation 4.1, Henk Granzier
• MGI ID: MGI:6283338
• Synonyms: Ttn^{deltaex112-158}
• Gene: Ttn Location: Chr2:76534324-76812891 bp, - strand Genetic Position: Chr2, 45.13 cM, cytoband D
• Alliance: Ttn^tm4.1Hgra page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:271832
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutations: Insertion, Intragenic deletion

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ttn Mutation: 1455 strains or lines available

References

• Original: J:271832 Brynnel A, et al., Downsizing the molecular spring of the giant protein titin reveals that skeletal muscle titin determines passive stiffness and drives longitudinal hypertrophy. Elife. 2018 Dec 19;7:e40532
• All: 2 reference(s)