Gimap3^tm1Yout
Targeted Allele Detail

Summary

• Symbol: Gimap3^tm1Yout
• Name: GTPase, IMAP family member 3; targeted mutation 1, Yousuke Takahama
• MGI ID: MGI:6280696
• Synonyms: Gimap3^MT
• Gene: Gimap3 Location: Chr6:48741398-48747785 bp, - strand Genetic Position: Chr6, 23.72 cM
• Alliance: Gimap3^tm1Yout page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209926
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site flanked neomycin resistance gene cassette was inserted into intron 3 (upstream of the first coding exon) and a third loxP site was inserted into the 3' UTR. This creates a conditional-ready allele with the entire coding region floxed. (J:209926)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gimap3 Mutation: 26 strains or lines available

References

• Original: J:209926 Yano K, et al., Gimap3 and Gimap5 cooperate to maintain T-cell numbers in the mouse. Eur J Immunol. 2014 Feb;44(2):561-72
• All: 1 reference(s)