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Tg(tetO-Vpr)L4Kopp
Transgene Detail
Summary
Symbol: Tg(tetO-Vpr)L4Kopp
Name: transgene insertion L4, Jeffrey Kopp
MGI ID: MGI:6272817
Synonyms: tet-op/Vpr
Transgene: Tg(tetO-Vpr)L4Kopp  Location: unknown  
Alliance: Tg(tetO-Vpr)L4Kopp page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsThe Vpr gene derived from the HIV-1 proviral clone pNL43 was inserted 3 to a tetracycline response operon promoter element (tet-op), with transcription initiation from the cytomegalovirus (CMV) promoter. Three transgenic lines were established, L2, L3, and L4. (J:116927)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:116927 Balasubramanyam A, et al., Effects of transgenic expression of HIV-1 Vpr on lipid and energy metabolism in mice. Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E40-8
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory