Tg(tetO-Vpr)L2Kopp
Transgene Detail

Summary

• Symbol: Tg(tetO-Vpr)L2Kopp
• Name: transgene insertion L2, Jeffrey Kopp
• MGI ID: MGI:6272813
• Synonyms: tet-op/Vpr
• Transgene: Tg(tetO-Vpr)L2Kopp Location: unknown
• Alliance: Tg(tetO-Vpr)L2Kopp page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The Vpr gene derived from the HIV-1 proviral clone pNL43 was inserted 3 to a tetracycline response operon promoter element (tet-op), with transcription initiation from the cytomegalovirus (CMV) promoter. Three transgenic lines were established, L2, L3, and L4. (J:116927)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:116927 Balasubramanyam A, et al., Effects of transgenic expression of HIV-1 Vpr on lipid and energy metabolism in mice. Am J Physiol Endocrinol Metab. 2007 Jan;292(1):E40-8
• All: 4 reference(s)