Tg(K14-Il33)1Kyam
Transgene Detail

Summary

• Symbol: Tg(K14-Il33)1Kyam
• Name: transgene insertion 1, Kiyofumi Yamanishi
• MGI ID: MGI:6272799
• Synonyms: hK14mIL33tg
• Transgene: Tg(K14-Il33)1Kyam Location: unknown
• Alliance: Tg(K14-Il33)1Kyam page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(K14-Il33)1Kyam expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Il33 (MGI:1924375)	mouse IL-33 variant 1 cDNA

• Mutation details: A 2-kb human keratin 14 promoter (GenBank accession no. AB091380.1), drives the transcription of a 0.6-kb 0.8-kb full-coding sequence of mouse IL-33 variant 1 cDNA. Two transgenic lines were established, but only one was studied further. (J:200678)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:200678 Imai Y, et al., Skin-specific expression of IL-33 activates group 2 innate lymphoid cells and elicits atopic dermatitis-like inflammation in mice. Proc Natl Acad Sci U S A. 2013 Aug 20;110(34):13921-6
• All: 3 reference(s)