Fam124bem1(IMPC)J
Endonuclease-mediated Allele Detail
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Symbol: |
Fam124bem1(IMPC)J |
Name: |
family with sequence similarity 124, member B; endonuclease-mediated mutation 1, Jackson |
MGI ID: |
MGI:6267298 |
Gene: |
Fam124b Location: Chr1:80176416-80192050 bp, - strand Genetic Position: Chr1, 41.19 cM
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Alliance: |
Fam124bem1(IMPC)J page
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IMPC: |
Fam124b gene page |
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Strain of Origin: |
C57BL/6NJ
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Project Collection: |
IMPC
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Allele Type: |
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Endonuclease-mediated (Null/knockout) |
Mutation: |
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Intragenic deletion
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Mutation details: This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TCAAGAGTTGGTTCAGTGGA and GCTGTAGTTTGGCACAGCAG, which resulted in a 2019 bp deletion beginning at Chromosome 1 position 80,198,618 bp and ending after 80,200,636 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000409540 (exon 2) and 176 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 244 and early truncation 27 amino acids later.
(J:188991)
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Inheritance: |
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Not Specified |
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Original: |
J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012; |
All: |
2 reference(s) |
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