Tut7^tm2.2Doca
Targeted Allele Detail

Summary

• Symbol: Tut7^tm2.2Doca
• Name: terminal uridylyl transferase 7; targeted mutation 2.2, Donal O'Carroll
• MGI ID: MGI:6259548
• Synonyms: Tut7^-
• Gene: Tut7 Location: Chr13:59919690-59971060 bp, - strand Genetic Position: Chr13, 31.88 cM
• Alliance: Tut7^tm2.2Doca page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:262343
• Parent Cell Line: A9 (ES Cell)
• Strain of Origin: (C57BL/6 x 129P2/OlaHsd)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 15. An additional loxP site was inserted downstream of exon 15. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 15. (J:262343)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tut7 Mutation: 68 strains or lines available

References

• Original: J:262343 Morgan M, et al., mRNA 3' uridylation and poly(A) tail length sculpt the mammalian maternal transcriptome. Nature. 2017 Aug 17;548(7667):347-351
• All: 2 reference(s)